Caveolin-1(−/−) Null Mammary Stromal Fibroblasts Share Characteristics with Human Breast Cancer-Associated Fibroblasts

Recently, we reported that human breast cancer-associated fibroblasts show functional inactivation of the retinoblastoma (RB) tumor suppressor and down-regulation of caveolin-1 (Cav-1) protein expression. However, it remains unknown whether loss of Cav-1 is sufficient to confer functional RB inactiv...

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Detalhes bibliográficos
Main Authors: Sotgia, Federica, Del Galdo, Francesco, Casimiro, Mathew C., Bonuccelli, Gloria, Mercier, Isabelle, Whitaker-Menezes, Diana, Daumer, Kristin M., Zhou, Jie, Wang, Chenguang, Katiyar, Sanjay, Xu, Huan, Bosco, Emily, Quong, Andrew A., Aronow, Bruce, Witkiewicz, Agnieszka K., Minetti, Carlo, Frank, Philippe G., Jimenez, Sergio A., Knudsen, Erik S., Pestell, Richard G., Lisanti, Michael P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2009
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2665737/
https://ncbi.nlm.nih.gov/pubmed/19234134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.080658
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