Human breast cancer-associated fibroblasts (CAFs) show caveolin-1 downregulation and RB tumor suppressor functional inactivation: Implications for the response to hormonal therapy

It is becoming increasingly apparent that the tumor microenvironment plays a critical role in human breast cancer onset and progression. Therefore, we isolated cancer-associated fibroblasts (CAFs) from human breast cancer lesions and studied their properties, as compared with normal mammary fibrobla...

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Detalhes bibliográficos
Publicado no:Cancer Biol Ther
Main Authors: Mercier, Isabelle, Casimiro, Mathew C., Wang, Chenguang, Rosenberg, Anne L., Quong, Judy, Minkeu, Alimatou, Allen, Kathleen G., Danilo, Christiane, Sotgia, Federica, Bonuccelli, Gloria, Jasmin, Jean-François, Xu, Huan, Bosco, Emily, Aronow, Bruce, Witkiewicz, Agnieszka, Pestell, Richard G., Knudsen, Erik S., Lisanti, Michael P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6688494/
https://ncbi.nlm.nih.gov/pubmed/18458534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.7.8.6220
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