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p120 Catenin Recruits Cadherins to γ-Secretase and Inhibits Production of Aβ Peptide
The γ-secretase complex cleaves many transmembrane proteins, including amyloid precursor protein, EphB and ErbB tyrosine kinase receptors, Notch1 receptors, and adhesion factors. Presenilin 1, the catalytic subunit of γ-secretase, associates with the cadherin/catenin cell-cell adhesion/communication...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2629097/ https://ncbi.nlm.nih.gov/pubmed/19008223 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M806250200 |
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