Cadherins Mediate Both the Association between PS1 and β-Catenin and the Effects of PS1 on β-Catenin Stability*

Presenilin1 (PS1), a protein involved in cellular development, forms functional complexes with β-catenin, a regulator of Wnt signaling and cell-cell adhesion. In addition, both proteins have been shown to play important roles in disease including cancer and Alzheimer disease. Although PS1 and β-cate...

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Autors principals: Serban, Geo, Kouchi, Zen, Baki, Lia, Georgakopoulos, Anastasios, Litterst, Claudia M., Shioi, Junichi, Robakis, Nikolaos K.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2005
Matèries:
Protein Synthesis, Post-Translation Modification, and Degradation
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4005066/
https://ncbi.nlm.nih.gov/pubmed/16126725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M507503200
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