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Metalloproteinase/Presenilin1 processing of ephrinB regulates EphB-induced Src phosphorylation and signaling

Bidirectional signaling triggered by interacting ephrinB receptors (EphB) and ephrinB ligands is crucial for development and function of the vascular and nervous systems. A signaling cascade triggered by this interaction involves activation of Src kinase and phosphorylation of ephrinB. The mechanism...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Georgakopoulos, Anastasios, Litterst, Claudia, Ghersi, Enrico, Baki, Lia, Xu, ChiJie, Serban, Geo, Robakis, Nikolaos K
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2006
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1422162/
https://ncbi.nlm.nih.gov/pubmed/16511561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601031
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