Presenilin1/γ-secretase promotes the EphB2-induced phosphorylation of ephrinB2 by regulating phosphoprotein associated with glycosphingolipid-enriched microdomains/Csk binding protein

Reverse signaling through the ephrinB ligands is important for several morphogenetic events, such as axon guidance, neuronal plasticity, spine maturation, and synaptogenesis. Signaling is initiated by binding of EphB receptors to ephrinB ligands, stimulating their tyrosine phosphorylation via an unc...

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Detalhes bibliográficos
Principais autores: Georgakopoulos, Anastasios, Xu, Jindong, Xu, Chijie, Mauger, Gweltas, Barthet, Gael, Robakis, Nikolaos K.
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2011
Assuntos:
Research Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3177584/
https://ncbi.nlm.nih.gov/pubmed/21746865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.11-187856
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