Clinical improvement by farnesyltransferase inhibition in NK large granular lymphocyte leukemia associated with imbalanced NK receptor signaling

Large granular lymphocyte (LGL) leukemia is commonly associated with poor hematopoiesis. The first case of pulmonary artery hypertension (PAH) was observed in a 57-year-old woman with natural killer (NK)–LGL leukemia and transfusion-dependent anemia. Using a genetic approach, we demonstrated that ki...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Epling-Burnette, P. K., Sokol, Lubomir, Chen, Xianhong, Bai, Fanqi, Zhou, Junmin, Blaskovich, Michelle A., Zou, JianXiang, Painter, Jeffrey S., Edwards, Todd D., Moscinski, Lynn, Yoder, Jeffrey A., Djeu, Julie Y., Sebti, Said, Loughran, Thomas P., Wei, Sheng
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society of Hematology 2008
Gaiak:
Neoplasia
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597136/
https://ncbi.nlm.nih.gov/pubmed/18791165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-02-136382
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