Clinical improvement by farnesyltransferase inhibition in NK large granular lymphocyte leukemia associated with imbalanced NK receptor signaling

Large granular lymphocyte (LGL) leukemia is commonly associated with poor hematopoiesis. The first case of pulmonary artery hypertension (PAH) was observed in a 57-year-old woman with natural killer (NK)–LGL leukemia and transfusion-dependent anemia. Using a genetic approach, we demonstrated that ki...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Epling-Burnette, P. K., Sokol, Lubomir, Chen, Xianhong, Bai, Fanqi, Zhou, Junmin, Blaskovich, Michelle A., Zou, JianXiang, Painter, Jeffrey S., Edwards, Todd D., Moscinski, Lynn, Yoder, Jeffrey A., Djeu, Julie Y., Sebti, Said, Loughran, Thomas P., Wei, Sheng
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society of Hematology 2008
विषय:
Neoplasia
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597136/
https://ncbi.nlm.nih.gov/pubmed/18791165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-02-136382
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