Reduced natural killer (NK) function associated with high-risk myelodysplastic syndrome (MDS) and reduced expression of activating NK receptors

Myelodysplastic syndromes (MDS) are characterized by ineffective hematopoiesis with potential for progression to acute myeloid leukemia (AML). We compared natural killer (NK) cytolytic function in 48 MDS patients with 37 healthy donors and found reduced activity in the patient population (K562 cytol...

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Main Authors: Epling-Burnette, Pearlie K., Bai, Fanqi, Painter, Jeffrey S., Rollison, Dana E., Salih, Helmut R., Krusch, Matthias, Zou, JianXiang, Ku, Edna, Zhong, Bin, Boulware, David, Moscinski, Lynn, Wei, Sheng, Djeu, Julie Y., List, Alan F.
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Hematology 2007
Assuntos:
Immunobiology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1885518/
https://ncbi.nlm.nih.gov/pubmed/17341666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-07-035519
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