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Effector memory regulatory T-cell expansion marks a pivotal point of immune escape in myelodysplastic syndromes
Myleodysplastic syndromes (MDS) are pre-malignant hematopoietic diseases that can progress to acute myeloid leukemia (AML) progression in conjunction with changes in immune function. In this model of leukemia evolution, the expansion of immunosuppressive regulatory T cells (Tregs) contributes to imm...
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Format: | Artigo |
Jezik: | Inglês |
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Landes Bioscience
2013
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Teme: | |
Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3601152/ https://ncbi.nlm.nih.gov/pubmed/23524348 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.22654 |
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