The effects of 5-azacytidine on the function and number of regulatory T cells and T-effectors in myelodysplastic syndrome

Expansion of regulatory T cells occurs in high-risk myelodysplastic syndrome and correlates with a poor prognosis. DNA methyltransferase inhibitors, particularly 5-azacytidine, have been shown to increase the survival of patients with high-risk myelodysplastic syndrome. It is not entirely clear whet...

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Hlavní autoři: Costantini, Benedetta, Kordasti, Shahram Y., Kulasekararaj, Austin G., Jiang, Jie, Seidl, Thomas, Abellan, Pilar Perez, Mohamedali, Azim, Thomas, Nicolas Shaun B., Farzaneh, Farzin, Mufti, Ghulam J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Ferrata Storti Foundation 2013
Témata:
Original Articles and Brief Reports
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3729899/
https://ncbi.nlm.nih.gov/pubmed/23242597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2012.074823
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