Somatic mutations identify a subgroup of aplastic anemia patients who progress to myelodysplastic syndrome

The distinction between acquired aplastic anemia (AA) and hypocellular myelodysplastic syndrome (hMDS) is often difficult, especially nonsevere AA. We postulated that somatic mutations are present in a subset of AA, and predict malignant transformation. From our database, we identified 150 AA patien...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Kulasekararaj, Austin G., Jiang, Jie, Smith, Alexander E., Mohamedali, Azim M., Mian, Syed, Gandhi, Shreyans, Gaken, Joop, Czepulkowski, Barbara, Marsh, Judith C. W., Mufti, Ghulam J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2014
Assuntos:
Myeloid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4383793/
https://ncbi.nlm.nih.gov/pubmed/25139356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-05-574889
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