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STAT3 mutations indicate the presence of subclinical T-cell clones in a subset of aplastic anemia and myelodysplastic syndrome patients

Large granular lymphocyte leukemia (LGL) is often associated with immune cytopenias and can cooccur in the context of aplastic anemia (AA) and myelodysplastic syndromes (MDS). We took advantage of the recent description of signal transducer and activator of transcription 3 (STAT3) mutations in LGL c...

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Bibliographic Details
Main Authors: Jerez, Andres, Clemente, Michael J., Makishima, Hideki, Rajala, Hanna, Gómez-Seguí, Ines, Olson, Thomas, McGraw, Kathy, Przychodzen, Bartlomiej, Kulasekararaj, Austin, Afable, Manuel, Husseinzadeh, Holleh D., Hosono, Naoko, LeBlanc, Francis, Lagström, Sonja, Zhang, Dan, Ellonen, Pekka, Tichelli, André, Nissen, Catherine, Lichtin, Alan E., Wodnar-Filipowicz, Aleksandra, Mufti, Ghulam J., List, Alan F., Mustjoki, Satu, Loughran, Thomas P., Maciejewski, Jaroslaw P.
Format: Artigo
Language:Inglês
Published: American Society of Hematology 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3790512/
https://ncbi.nlm.nih.gov/pubmed/23926297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-04-494930
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