STAT5b in LGL leukemia – a novel therapeutic target?

Por Rajala, Hanna L. M., Mustjoki, Satu
Publicado em 2013

A novel class of somatic mutations in blood detected preferentially in CD8 + cells

Por Valori, Miko, Jansson, Lilja, Kiviharju, Anna, Ellonen, Pekka, Rajala, Hanna, Awad, Shady Adnan, Mustjoki, Satu, Tienari, Pentti J.
Publicado no Clin Immunol (2017)

Deep sequencing of the T-cell receptor repertoire in CD8(+) T-large granular lymphocyte leukemia identifies signature landscapes

Por Clemente, Michael J., Przychodzen, Bartlomiej, Jerez, Andres, Dienes, Brittney E., Afable, Manuel G., Husseinzadeh, Holleh, Rajala, Hanna L. M., Wlodarski, Marcin W., Mustjoki, Satu, Maciejewski, Jaroslaw P.
Publicado em 2013

Immunosuppressive Therapy of LGL Leukemia: Prospective Multicenter Phase II Study by the Eastern Cooperative Oncology Group (E5998)

Por Loughran, Thomas P., Zickl, Lynette, Olson, Thomas L., Wang, Victoria, Zhang, Dan, Rajala, Hanna L.M., Hasanali, Zainul, Bennett, John M., Lazarus, Hillard M., Litzow, Mark R., Evens, Andrew M., Mustjoki, Satu, Tallman, Martin S.
Publicado no Leukemia (2014)

Activating somatic mutations outside the SH2-domain of STAT3 in LGL-Leukemia

Por Andersson, Emma, Kuusanmäki, Heikki, Bortoluzzi, Sabrina, Lagström, Sonja, Parsons, Alun, Rajala, Hanna, van Adrichem, Arjan, Eldfors, Samuli, Olson, Thomas, Clemente, Michael J., Laasonen, Anu, Ellonen, Pekka, Heckman, Caroline, Loughran, Thomas P., Maciejewski, Jaroslaw P., Mustjoki, Satu
Publicado no Leukemia (2015)

The analysis of clonal diversity and therapy responses using STAT3 mutations as a molecular marker in large granular lymphocytic leukemia

Por Rajala, Hanna L. M., Olson, Thomas, Clemente, Michael J., Lagström, Sonja, Ellonen, Pekka, Lundan, Tuija, Hamm, David E., Zaman, Syed Arshi Uz, Lopez Marti, Jesus M., Andersson, Emma I., Jerez, Andres, Porkka, Kimmo, Maciejewski, Jaroslaw P., Loughran, Thomas P., Mustjoki, Satu
Publicado no Haematologica (2015)

Discovery of somatic STAT5b mutations in large granular lymphocytic leukemia

Por Rajala, Hanna L. M., Eldfors, Samuli, Kuusanmäki, Heikki, van Adrichem, Arjan J., Olson, Thomas, Lagström, Sonja, Andersson, Emma I., Jerez, Andres, Clemente, Michael J., Yan, Yiyi, Zhang, Dan, Awwad, Andy, Ellonen, Pekka, Kallioniemi, Olli, Wennerberg, Krister, Porkka, Kimmo, Maciejewski, Jaroslaw P., Loughran, Thomas P., Heckman, Caroline, Mustjoki, Satu
Publicado em 2013

Activating germline mutations in STAT3 cause early-onset multi-organ autoimmune disease

Por Flanagan, Sarah E., Haapaniemi, Emma, Russell, Mark A., Caswell, Richard, Allen, Hana Lango, De Franco, Elisa, McDonald, Timothy J., Rajala, Hanna, Ramelius, Anita, Barton, John, Heiskanen, Kaarina, Heiskanen-Kosma, Tarja, Kajosaari, Merja, Murphy, Nuala P., Milenkovic, Tatjana, Seppänen, Mikko, Lernmark, Åke, Mustjoki, Satu, Otonkoski, Timo, Kere, Juha, Morgan, Noel G., Ellard, Sian, Hattersley, Andrew T.
Publicado em 2014

STAT3 mutations indicate the presence of subclinical T-cell clones in a subset of aplastic anemia and myelodysplastic syndrome patients

Por Jerez, Andres, Clemente, Michael J., Makishima, Hideki, Rajala, Hanna, Gómez-Seguí, Ines, Olson, Thomas, McGraw, Kathy, Przychodzen, Bartlomiej, Kulasekararaj, Austin, Afable, Manuel, Husseinzadeh, Holleh D., Hosono, Naoko, LeBlanc, Francis, Lagström, Sonja, Zhang, Dan, Ellonen, Pekka, Tichelli, André, Nissen, Catherine, Lichtin, Alan E., Wodnar-Filipowicz, Aleksandra, Mufti, Ghulam J., List, Alan F., Mustjoki, Satu, Loughran, Thomas P., Maciejewski, Jaroslaw P.
Publicado em 2013

Autoimmunity, hypogammaglobulinemia, lymphoproliferation, and mycobacterial disease in patients with activating mutations in STAT3

Por Haapaniemi, Emma M., Kaustio, Meri, Rajala, Hanna L. M., van Adrichem, Arjan J., Kainulainen, Leena, Glumoff, Virpi, Doffinger, Rainer, Kuusanmäki, Heikki, Heiskanen-Kosma, Tarja, Trotta, Luca, Chiang, Samuel, Kulmala, Petri, Eldfors, Samuli, Katainen, Riku, Siitonen, Sanna, Karjalainen-Lindsberg, Marja-Liisa, Kovanen, Panu E., Otonkoski, Timo, Porkka, Kimmo, Heiskanen, Kaarina, Hänninen, Arno, Bryceson, Yenan T., Uusitalo-Seppälä, Raija, Saarela, Janna, Seppänen, Mikko, Mustjoki, Satu, Kere, Juha
Publicado no Blood (2015)