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Deep sequencing of the T-cell receptor repertoire in CD8(+) T-large granular lymphocyte leukemia identifies signature landscapes
New massively parallel sequencing technology enables, through deep sequencing of rearranged T-cell receptor (TCR) Vβ complementarity-determining region 3 (CDR3) regions, a previously inaccessible level of TCR repertoire analysis. The CDR3 repertoire diversity reflects clonal composition, the potenti...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3862272/ https://ncbi.nlm.nih.gov/pubmed/24149287 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-05-506386 |
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