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Discovery of somatic STAT5b mutations in large granular lymphocytic leukemia
Large granular lymphocytic (LGL) leukemia is characterized by clonal expansion of cytotoxic T cells or natural killer cells. Recently, somatic mutations in the signal transducer and activator of transcription 3 (STAT3) gene were discovered in 28% to 40% of LGL leukemia patients. By exome and transcr...
Αποθηκεύτηκε σε:
Κύριοι συγγραφείς: | , , , , , , , , , , , , , , , , , , , |
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Μορφή: | Artigo |
Γλώσσα: | Inglês |
Έκδοση: |
American Society of Hematology
2013
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Θέματα: | |
Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3668487/ https://ncbi.nlm.nih.gov/pubmed/23596048 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-12-474577 |
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