Discovery of somatic STAT5b mutations in large granular lymphocytic leukemia

Large granular lymphocytic (LGL) leukemia is characterized by clonal expansion of cytotoxic T cells or natural killer cells. Recently, somatic mutations in the signal transducer and activator of transcription 3 (STAT3) gene were discovered in 28% to 40% of LGL leukemia patients. By exome and transcr...

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Bibliografiske detaljer
Main Authors: Rajala, Hanna L. M., Eldfors, Samuli, Kuusanmäki, Heikki, van Adrichem, Arjan J., Olson, Thomas, Lagström, Sonja, Andersson, Emma I., Jerez, Andres, Clemente, Michael J., Yan, Yiyi, Zhang, Dan, Awwad, Andy, Ellonen, Pekka, Kallioniemi, Olli, Wennerberg, Krister, Porkka, Kimmo, Maciejewski, Jaroslaw P., Loughran, Thomas P., Heckman, Caroline, Mustjoki, Satu
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2013
Fag:
Lymphoid Neoplasia
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3668487/
https://ncbi.nlm.nih.gov/pubmed/23596048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-12-474577
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