Somatic STAT3 Mutations in Large Granular Lymphocytic Leukemia

BACKGROUND: T-cell large granular lymphocytic leukemia is a rare lymphoproliferative disorder characterized by the expansion of clonal CD3+CD8+ cytotoxic T lymphocytes (CTLs) and often associated with autoimmune disorders and immune-mediated cytopenias. METHODS: We used next-generation exome sequenc...

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Bibliografski detalji
Glavni autori: Koskela, Hanna L.M., Eldfors, Samuli, Ellonen, Pekka, van Adrichem, Arjan J., Kuusanmäki, Heikki, Andersson, Emma I., Lagström, Sonja, Clemente, Michael J., Olson, Thomas, Jalkanen, Sari E., Majumder, Muntasir Mamun, Almusa, Henrikki, Edgren, Henrik, Lepistö, Maija, Mattila, Pirkko, Guinta, Kathryn, Koistinen, Pirjo, Kuittinen, Taru, Penttinen, Kati, Parsons, Alun, Knowles, Jonathan, Saarela, Janna, Wennerberg, Krister, Kallioniemi, Olli, Porkka, Kimmo, Loughran, Thomas P., Heckman, Caroline A., Maciejewski, Jaroslaw P., Mustjoki, Satu
Format: Artigo
Jezik:Inglês
Izdano: 2012
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3693860/
https://ncbi.nlm.nih.gov/pubmed/22591296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1114885
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