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Somatic STAT3 Mutations in Large Granular Lymphocytic Leukemia
BACKGROUND: T-cell large granular lymphocytic leukemia is a rare lymphoproliferative disorder characterized by the expansion of clonal CD3+CD8+ cytotoxic T lymphocytes (CTLs) and often associated with autoimmune disorders and immune-mediated cytopenias. METHODS: We used next-generation exome sequenc...
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| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3693860/ https://ncbi.nlm.nih.gov/pubmed/22591296 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1114885 |
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