Deep sequencing of the T-cell receptor repertoire in CD8(+) T-large granular lymphocyte leukemia identifies signature landscapes

New massively parallel sequencing technology enables, through deep sequencing of rearranged T-cell receptor (TCR) Vβ complementarity-determining region 3 (CDR3) regions, a previously inaccessible level of TCR repertoire analysis. The CDR3 repertoire diversity reflects clonal composition, the potenti...

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Bibliografiska uppgifter
Huvudupphovsmän: Clemente, Michael J., Przychodzen, Bartlomiej, Jerez, Andres, Dienes, Brittney E., Afable, Manuel G., Husseinzadeh, Holleh, Rajala, Hanna L. M., Wlodarski, Marcin W., Mustjoki, Satu, Maciejewski, Jaroslaw P.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society of Hematology 2013
Ämnen:
Lymphoid Neoplasia
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3862272/
https://ncbi.nlm.nih.gov/pubmed/24149287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-05-506386
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