Spliceosome mutations exhibit specific associations with epigenetic modifiers and proto-oncogenes mutated in myelodysplastic syndrome

The recent identification of acquired mutations in key components of the spliceosome machinery strongly implicates abnormalities of mRNA splicing in the pathogenesis of myelodysplastic syndromes. However, questions remain as to how these aberrations functionally combine with the growing list of muta...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Mian, Syed A., Smith, Alexander E., Kulasekararaj, Austin G., Kizilors, Aytug, Mohamedali, Azim M., Lea, Nicholas C., Mitsopoulos, Konstantinos, Ford, Kevin, Nasser, Erick, Seidl, Thomas, Mufti, Ghulam J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Ferrata Storti Foundation 2013
Gaiak:
Original Articles and Brief Reports
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3696609/
https://ncbi.nlm.nih.gov/pubmed/23300180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2012.075325
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