Spliceosome mutations exhibit specific associations with epigenetic modifiers and proto-oncogenes mutated in myelodysplastic syndrome

The recent identification of acquired mutations in key components of the spliceosome machinery strongly implicates abnormalities of mRNA splicing in the pathogenesis of myelodysplastic syndromes. However, questions remain as to how these aberrations functionally combine with the growing list of muta...

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Detalhes bibliográficos
Main Authors: Mian, Syed A., Smith, Alexander E., Kulasekararaj, Austin G., Kizilors, Aytug, Mohamedali, Azim M., Lea, Nicholas C., Mitsopoulos, Konstantinos, Ford, Kevin, Nasser, Erick, Seidl, Thomas, Mufti, Ghulam J.
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2013
Assuntos:
Original Articles and Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3696609/
https://ncbi.nlm.nih.gov/pubmed/23300180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2012.075325
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