Spliceosome mutations exhibit specific associations with epigenetic modifiers and proto-oncogenes mutated in myelodysplastic syndrome

The recent identification of acquired mutations in key components of the spliceosome machinery strongly implicates abnormalities of mRNA splicing in the pathogenesis of myelodysplastic syndromes. However, questions remain as to how these aberrations functionally combine with the growing list of muta...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Mian, Syed A., Smith, Alexander E., Kulasekararaj, Austin G., Kizilors, Aytug, Mohamedali, Azim M., Lea, Nicholas C., Mitsopoulos, Konstantinos, Ford, Kevin, Nasser, Erick, Seidl, Thomas, Mufti, Ghulam J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Ferrata Storti Foundation 2013
Pynciau:
Original Articles and Brief Reports
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3696609/
https://ncbi.nlm.nih.gov/pubmed/23300180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2012.075325
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