Spliceosome mutations exhibit specific associations with epigenetic modifiers and proto-oncogenes mutated in myelodysplastic syndrome

The recent identification of acquired mutations in key components of the spliceosome machinery strongly implicates abnormalities of mRNA splicing in the pathogenesis of myelodysplastic syndromes. However, questions remain as to how these aberrations functionally combine with the growing list of muta...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Mian, Syed A., Smith, Alexander E., Kulasekararaj, Austin G., Kizilors, Aytug, Mohamedali, Azim M., Lea, Nicholas C., Mitsopoulos, Konstantinos, Ford, Kevin, Nasser, Erick, Seidl, Thomas, Mufti, Ghulam J.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Ferrata Storti Foundation 2013
Θέματα:
Original Articles and Brief Reports
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3696609/
https://ncbi.nlm.nih.gov/pubmed/23300180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2012.075325
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