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A critical role for DAP10 and DAP12 in CD8(+) T cell–mediated tissue damage in large granular lymphocyte leukemia
Large granular lymphocyte (LGL) leukemia, or LGLL, is characterized by increased numbers of circulating clonal LGL cells in association with neutropenia, anemia, rheumatoid arthritis, and pulmonary artery hypertension (PAH). Emerging evidence suggests that LGLL cells with a CD8(+)CD28(null) phenotyp...
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| Main Authors: | , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2665892/ https://ncbi.nlm.nih.gov/pubmed/19075187 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-07-168245 |
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