Multiple autophosphorylation sites are dispensable for murine ATM activation in vivo

Cellular responses to both physiological and pathological DNA double-strand breaks are initiated through activation of the evolutionarily conserved ataxia telangiectasia mutated (ATM) kinase. Upon DNA damage, an activation mechanism involving autophosphorylation has been reported to allow ATM to pho...

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Detaylı Bibliyografya
Asıl Yazarlar: Daniel, Jeremy A., Pellegrini, Manuela, Lee, Ji-Hoon, Paull, Tanya T., Feigenbaum, Lionel, Nussenzweig, André
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Rockefeller University Press 2008
Konular:
Research Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2592823/
https://ncbi.nlm.nih.gov/pubmed/19047460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200805154
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