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Mitochondria at the crossroads of ATM-mediated stress signaling and regulation of reactive oxygen species

The Ataxia-telangiectasia mutated (ATM) kinase responds to DNA double-strand breaks and other forms of cellular stress, including reactive oxygen species (ROS). Recent work in the field has uncovered links between mitochondrial ROS and ATM activation, suggesting that ATM acts as a sensor for mitocho...

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Publicado en:Redox Biol
Main Authors: Lee, Ji-Hoon, Paull, Tanya T.
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7115119/
https://ncbi.nlm.nih.gov/pubmed/32244177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2020.101511
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