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Involvement of novel autophosphorylation sites in ATM activation
ATM kinase plays a central role in signaling DNA double-strand breaks to cell cycle checkpoints and to the DNA repair machinery. Although the exact mechanism of ATM activation remains unknown, efficient activation requires the Mre11 complex, autophosphorylation on S1981 and the involvement of protei...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2006
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1538573/ https://ncbi.nlm.nih.gov/pubmed/16858402 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601231 |
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