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Reactive Oxygen Species (ROS)-Activated ATM-Dependent Phosphorylation of Cytoplasmic Substrates Identified by Large-Scale Phosphoproteomics Screen

Ataxia-telangiectasia, mutated (ATM) protein plays a central role in phosphorylating a network of proteins in response to DNA damage. These proteins function in signaling pathways designed to maintain the stability of the genome and minimize the risk of disease by controlling cell cycle checkpoints,...

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Detalhes bibliográficos
Publicado no:Mol Cell Proteomics
Main Authors: Kozlov, Sergei V., Waardenberg, Ashley J., Engholm-Keller, Kasper, Arthur, Jonathan W., Graham, Mark E., Lavin, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4813686/
https://ncbi.nlm.nih.gov/pubmed/26699800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M115.055723
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