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ATM signals to TSC2 in the cytoplasm to regulate mTORC1 in response to ROS
Ataxia-telangiectasia mutated (ATM) is a cellular damage sensor that coordinates the cell cycle with damage-response checkpoints and DNA repair to preserve genomic integrity. However, ATM also has been implicated in metabolic regulation, and ATM deficiency is associated with elevated reactive oxygen...
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| Autors principals: | , , , , , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2840158/ https://ncbi.nlm.nih.gov/pubmed/20160076 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0913860107 |
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