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TSC1/TSC2 and Rheb have different effects on TORC1 and TORC2 activity
Target of rapamycin (TOR) plays a central role in cell growth regulation by integrating signals from growth factors, nutrients, and cellular energy levels. TOR forms two distinct physical and functional complexes, termed TOR complex 1 (TORC1) and TOR complex 2 (TORC2). TORC1, which is sensitive to r...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2006
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1458976/ https://ncbi.nlm.nih.gov/pubmed/16627617 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0602282103 |
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