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Biochemical and Functional Characterizations of Small GTPase Rheb and TSC2 GAP Activity
Tuberous sclerosis complex (TSC) is a genetic disease caused by a mutation in either the tsc1 or tsc2 tumor suppressor gene. Recent studies have demonstrated that TSC2 displays GAP (GTPase-activating protein) activity specifically towards the small G protein Rheb and inhibits its ability to stimulat...
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| Main Authors: | , , |
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| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
American Society for Microbiology
2004
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC515062/ https://ncbi.nlm.nih.gov/pubmed/15340059 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.18.7965-7975.2004 |
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