Autophosphorylation at serine 1981 stabilizes ATM at DNA damage sites

Ataxia telangiectasia mutated (ATM) plays a critical role in the cellular response to DNA damage. In response to DNA double-strand breaks (DSBs), ATM is autophosphorylated at serine 1981. Although this autophosphorylation is widely considered a sign of ATM activation, it is still not clear if autoph...

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Bibliographic Details
Main Authors: So, Sairei, Davis, Anthony J., Chen, David J.
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2009
Subjects:
Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2806275/
https://ncbi.nlm.nih.gov/pubmed/20026654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200906064
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