BRCA1 modulates the autophosphorylation status of DNA-PKcs in S phase of the cell cycle

Non-homologous end-joining (NHEJ) and homologous recombination (HR) are the two prominent pathways responsible for the repair of DNA double-strand breaks (DSBs). NHEJ is not restricted to a cell-cycle stage, whereas HR is active primarily in the S/G2 phases suggesting there are cell cycle-specific m...

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Hlavní autoři: Davis, Anthony J., Chi, Linfeng, So, Sairei, Lee, Kyung-Jong, Mori, Eiichiro, Fattah, Kazi, Yang, Jun, Chen, David J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2014
Témata:
Genome Integrity, Repair and Replication
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4191403/
https://ncbi.nlm.nih.gov/pubmed/25223785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku824
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