Autophosphorylation and ATM Activation: ADDITIONAL SITES ADD TO THE COMPLEXITY

The recognition and signaling of DNA double strand breaks involves the participation of multiple proteins, including the protein kinase ATM (mutated in ataxia-telangiectasia). ATM kinase is activated in the vicinity of the break and is recruited to the break site by the Mre11-Rad50-Nbs1 complex, whe...

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Detalhes bibliográficos
Main Authors: Kozlov, Sergei V., Graham, Mark E., Jakob, Burkhard, Tobias, Frank, Kijas, Amanda W., Tanuji, Marcel, Chen, Philip, Robinson, Phillip J., Taucher-Scholz, Gisela, Suzuki, Keiji, So, Sairai, Chen, David, Lavin, Martin F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3059052/
https://ncbi.nlm.nih.gov/pubmed/21149446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.204065
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