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Multiple autophosphorylation sites are dispensable for murine ATM activation in vivo
Cellular responses to both physiological and pathological DNA double-strand breaks are initiated through activation of the evolutionarily conserved ataxia telangiectasia mutated (ATM) kinase. Upon DNA damage, an activation mechanism involving autophosphorylation has been reported to allow ATM to pho...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Rockefeller University Press
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2592823/ https://ncbi.nlm.nih.gov/pubmed/19047460 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200805154 |
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