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Multiple autophosphorylation sites are dispensable for murine ATM activation in vivo

Cellular responses to both physiological and pathological DNA double-strand breaks are initiated through activation of the evolutionarily conserved ataxia telangiectasia mutated (ATM) kinase. Upon DNA damage, an activation mechanism involving autophosphorylation has been reported to allow ATM to pho...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Daniel, Jeremy A., Pellegrini, Manuela, Lee, Ji-Hoon, Paull, Tanya T., Feigenbaum, Lionel, Nussenzweig, André
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: The Rockefeller University Press 2008
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2592823/
https://ncbi.nlm.nih.gov/pubmed/19047460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200805154
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