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Glutathione Reductase Targeted to Type II Cells Does Not Protect Mice from Hyperoxic Lung Injury
Exposure of the lung epithelium to reactive oxygen species without adequate antioxidant defenses leads to airway inflammation, and may contribute to lung injury. Glutathione peroxidase catalyzes the reduction of peroxides by oxidation of glutathione (GSH) to glutathione disulfide (GSSG), which can i...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Thoracic Society
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2586044/ https://ncbi.nlm.nih.gov/pubmed/18566333 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2008-0112OC |
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