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Glutathione Reductase Targeted to Type II Cells Does Not Protect Mice from Hyperoxic Lung Injury

Exposure of the lung epithelium to reactive oxygen species without adequate antioxidant defenses leads to airway inflammation, and may contribute to lung injury. Glutathione peroxidase catalyzes the reduction of peroxides by oxidation of glutathione (GSH) to glutathione disulfide (GSSG), which can i...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Heyob, Kathryn M., Rogers, Lynette K., Welty, Stephen E.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Thoracic Society 2008
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2586044/
https://ncbi.nlm.nih.gov/pubmed/18566333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2008-0112OC
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