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Nfib hemizygous mice are protected from hyperoxic lung injury and death

Nuclear Factor I (Nfi) genes encode transcription factors essential for the development of organ systems including the lung. Nfib null mice die at birth with immature lungs. Nfib hemizygous mice have reduced lung maturation with decreased survival. We therefore hypothesized that these mice would be...

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Detalhes bibliográficos
Publicado no:Physiol Rep
Main Authors: Kumar, Vasantha H. S., Chaker El Khoury, Joseph, Gronostajski, Richard, Wang, Huamei, Nielsen, Lori, Ryan, Rita M.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5582271/
https://ncbi.nlm.nih.gov/pubmed/28830981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.13398
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