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Nfib hemizygous mice are protected from hyperoxic lung injury and death

Nuclear Factor I (Nfi) genes encode transcription factors essential for the development of organ systems including the lung. Nfib null mice die at birth with immature lungs. Nfib hemizygous mice have reduced lung maturation with decreased survival. We therefore hypothesized that these mice would be...

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Bibliographische Detailangaben
Veröffentlicht in:Physiol Rep
Hauptverfasser: Kumar, Vasantha H. S., Chaker El Khoury, Joseph, Gronostajski, Richard, Wang, Huamei, Nielsen, Lori, Ryan, Rita M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5582271/
https://ncbi.nlm.nih.gov/pubmed/28830981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.13398
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