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Nfib hemizygous mice are protected from hyperoxic lung injury and death

Nuclear Factor I (Nfi) genes encode transcription factors essential for the development of organ systems including the lung. Nfib null mice die at birth with immature lungs. Nfib hemizygous mice have reduced lung maturation with decreased survival. We therefore hypothesized that these mice would be...

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Dettagli Bibliografici
Pubblicato in:Physiol Rep
Autori principali: Kumar, Vasantha H. S., Chaker El Khoury, Joseph, Gronostajski, Richard, Wang, Huamei, Nielsen, Lori, Ryan, Rita M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5582271/
https://ncbi.nlm.nih.gov/pubmed/28830981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.13398
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