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Nfib hemizygous mice are protected from hyperoxic lung injury and death

Nuclear Factor I (Nfi) genes encode transcription factors essential for the development of organ systems including the lung. Nfib null mice die at birth with immature lungs. Nfib hemizygous mice have reduced lung maturation with decreased survival. We therefore hypothesized that these mice would be...

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Detalles Bibliográficos
Publicado en:Physiol Rep
Autores principales: Kumar, Vasantha H. S., Chaker El Khoury, Joseph, Gronostajski, Richard, Wang, Huamei, Nielsen, Lori, Ryan, Rita M.
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5582271/
https://ncbi.nlm.nih.gov/pubmed/28830981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.13398
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