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Glutathione reductase deficiency alters lung development and hyperoxic responses in neonatal mice

Cellular antioxidants protect against hyperoxic lung injury. The role of the glutathione (GSH) system in lung development and bronchopulmonary dysplasia (BPD) pathogenesis has not been systematically investigated. The current study utilized GSH reductase-deficient (Gsr-KO) neonatal mice to test the...

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Bibliographic Details
Published in:Redox Biol
Main Authors: Robbins, Mary E., Cho, Hye-Youn, Hansen, Jason M., Luchsinger, Joseph R., Locy, Morgan L., Velten, Markus, Kleeberger, Steven R., Rogers, Lynette K., Tipple, Trent E.
Format: Artigo
Language:Inglês
Published: Elsevier 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7708869/
https://ncbi.nlm.nih.gov/pubmed/33254076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2020.101797
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