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Glutathione reductase deficiency alters lung development and hyperoxic responses in neonatal mice

Cellular antioxidants protect against hyperoxic lung injury. The role of the glutathione (GSH) system in lung development and bronchopulmonary dysplasia (BPD) pathogenesis has not been systematically investigated. The current study utilized GSH reductase-deficient (Gsr-KO) neonatal mice to test the...

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Bibliografische gegevens
Gepubliceerd in:Redox Biol
Hoofdauteurs: Robbins, Mary E., Cho, Hye-Youn, Hansen, Jason M., Luchsinger, Joseph R., Locy, Morgan L., Velten, Markus, Kleeberger, Steven R., Rogers, Lynette K., Tipple, Trent E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7708869/
https://ncbi.nlm.nih.gov/pubmed/33254076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2020.101797
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