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Thioredoxin-Related Mechanisms in Hyperoxic Lung Injury in Mice
Reduction of glutathione disulfide (GSSG) to glutathione (GSH) by glutathione reductase (GR) enhances the efficiency of GSH-dependent antioxidant activities. However, GR-deficient (a1Neu) mice are less susceptible to acute lung injury from continuous exposure to > 95% O(2) (96 h: 6.9 ± 0.1 g righ...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Thoracic Society
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2176120/ https://ncbi.nlm.nih.gov/pubmed/17575077 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2006-0376OC |
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