Thioredoxin-Related Mechanisms in Hyperoxic Lung Injury in Mice

Reduction of glutathione disulfide (GSSG) to glutathione (GSH) by glutathione reductase (GR) enhances the efficiency of GSH-dependent antioxidant activities. However, GR-deficient (a1Neu) mice are less susceptible to acute lung injury from continuous exposure to > 95% O(2) (96 h: 6.9 ± 0.1 g righ...

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Bibliographic Details
Main Authors: Tipple, Trent E., Welty, Stephen E., Rogers, Lynette K., Hansen, Thomas N., Choi, Young-Eun, Kehrer, James P., Smith, Charles V.
Format: Artigo
Language:Inglês
Published: American Thoracic Society 2007
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2176120/
https://ncbi.nlm.nih.gov/pubmed/17575077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2006-0376OC
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