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Glutathione Reductase Targeted to Type II Cells Does Not Protect Mice from Hyperoxic Lung Injury

Exposure of the lung epithelium to reactive oxygen species without adequate antioxidant defenses leads to airway inflammation, and may contribute to lung injury. Glutathione peroxidase catalyzes the reduction of peroxides by oxidation of glutathione (GSH) to glutathione disulfide (GSSG), which can i...

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Autores principales: Heyob, Kathryn M., Rogers, Lynette K., Welty, Stephen E.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Thoracic Society 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2586044/
https://ncbi.nlm.nih.gov/pubmed/18566333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2008-0112OC
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