A carregar...
Total Synthesis and Evaluation of [Ψ[CH(2)NH]Tpg(4)]Vancomycin Aglycon: Reengineering Vancomycin for Dual D-Ala-D-Ala and D-Ala-D-Lac Binding
An effective synthesis of [Ψ[CH(2)NH]Tpg(4)]vancomycin aglycon (5) is detailed in which the residue 4 amide carbonyl of vancomycin aglycon has been replaced with a methylene. This removal of a single atom was conducted to enhance binding to D-Ala-D-Lac countering resistance endowed to bacteria that...
Na minha lista:
| Main Authors: | , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2586002/ https://ncbi.nlm.nih.gov/pubmed/16506767 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja0572912 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|