Peripheral modifications of [Ψ[CH(2)NH]Tpg(4)]vancomycin with added synergistic mechanisms of action provide durable and potent antibiotics

Lignende værker

• Total Syntheses and Initial Evaluation of [Ψ[C(=S)NH]Tpg(4)]vancomycin, [Ψ[C(=NH)NH]Tpg(4)]vancomycin, [Ψ[CH(2)NH]Tpg(4)]vancomycin and their (4-Chlorobiphenyl)methyl Derivatives: Synergistic Binding Pocket and Peripheral Modifications for the Glycopeptide Antibiotics
  af: Okano, Akinori, et al.
  Udgivet: (2015)
• Total Synthesis of [Ψ[C(=S)NH]Tpg(4)]Vancomycin Aglycon, [Ψ[C(=NH)NH]Tpg(4)]Vancomycin Aglycon, and Related Key Compounds: Reengineering Vancomycin for Dual d-Ala-d-Ala and d-Ala-d-Lac Binding
  af: Xie, Jian, et al.
  Udgivet: (2012)
• Total Synthesis of [Ψ[C(=NH)NH]Tpg(4)]Vancomycin and its (4-Chlorobiphenyl)methyl Derivative: Impact of Peripheral Modifications on Vancomycin Analogues Redesigned for Dual d-Ala-d-Ala and d-Ala-d-Lac Binding
  af: Okano, Akinori, et al.
  Udgivet: (2014)
• Total Synthesis and Evaluation of [Ψ[CH(2)NH]Tpg(4)]Vancomycin Aglycon: Reengineering Vancomycin for Dual D-Ala-D-Ala and D-Ala-D-Lac Binding
  af: Crowley, Brendan M., et al.
  Udgivet: (2006)
• Total Syntheses of Vancomycin Related Glycopeptide Antibiotics and Key Analogues
  af: Okano, Akinori, et al.
  Udgivet: (2017)