Wordt geladen...

Peripheral modifications of [Ψ[CH(2)NH]Tpg(4)]vancomycin with added synergistic mechanisms of action provide durable and potent antibiotics

Subsequent to binding pocket modifications designed to provide dual d-Ala-d-Ala/d-Ala-d-Lac binding that directly overcome the molecular basis of vancomycin resistance, peripheral structural changes have been explored to improve antimicrobial potency and provide additional synergistic mechanisms of...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Okano, Akinori, Isley, Nicholas A., Boger, Dale L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2017
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5495262/
https://ncbi.nlm.nih.gov/pubmed/28559345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1704125114
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!