Lanean...
Peripheral modifications of [Ψ[CH(2)NH]Tpg(4)]vancomycin with added synergistic mechanisms of action provide durable and potent antibiotics
Subsequent to binding pocket modifications designed to provide dual d-Ala-d-Ala/d-Ala-d-Lac binding that directly overcome the molecular basis of vancomycin resistance, peripheral structural changes have been explored to improve antimicrobial potency and provide additional synergistic mechanisms of...
Gorde:
| Argitaratua izan da: | Proc Natl Acad Sci U S A |
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| Egile Nagusiak: | , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
National Academy of Sciences
2017
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5495262/ https://ncbi.nlm.nih.gov/pubmed/28559345 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1704125114 |
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