Genetic Ablation of M(3) Muscarinic Receptors Attenuates Murine Colon Epithelial Cell Proliferation and Neoplasia

Normal colon epithelial cells express and most colon cancers over-express M(3) muscarinic receptors (M(3)R). In human colon cancer cells, post-M(3)R signaling stimulates cell proliferation. To explore the importance of M(3)R expression in vivo we used the azoxymethane (AOM)-induced colon neoplasia m...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Raufman, Jean-Pierre, Samimi, Roxana, Shah, Nirish, Khurana, Sandeep, Shant, Jasleen, Drachenberg, Cinthia, Xie, Guofeng, Wess, Jürgen, Cheng, Kunrong
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2577901/
https://ncbi.nlm.nih.gov/pubmed/18483237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-07-6810
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky